Isotopically Labeled Compounds
Medchemexpress LLC Aprepitant-d4 5mg | 1133387-60-6 | 538.45 | C23H17D4F7N4O3 | 5 MG
Aprepitant-d4 is the deuterium-labeled analogue of aprepitant, supplied as a powder and intended for use as a stable isotope internal standard in research and analytical laboratories, particularly for LC-MS quantitation.
- Deuterium-labeled internal standard for quantitative LC-MS assays.
- High chemical purity (99.0%).
- Suitable molecular weight and isotopic composition for sensitive detection (MW 538.45).
- Supplied as a stable powder with recommended storage at -20°C for long-term stability.
- High solubility in DMSO (100 mg/mL); warming and sonication recommended.
Medchemexpress LLC Aldicarb (sulfone) | 1646-88-4 | 99.46% | 222.26 | 50 MG
Aldicarb sulfone is a metabolite of the carbamate pesticide Aldicarb, exhibiting insecticidal activity. It is also known to be a cholinesterase inhibitor.
- Inhibits egg hatching in *Tylenchulus semipenetrans*
- Reduces nematode motility
- Hindered male larval development
- Decreased plasma pseudocholinesterase levels in rats
- Decreased red blood cell cholinesterase levels in rats
Cayman Chemical 13 S-HODE-d4 50ug
An internal standard for the quantification of 13-HODE by GC- or LC-MS
Cayman Chemical NIfuroxazIde-d4 500ug
An internal standard for the quantification of nifuroxazide by GC- or LC-MS
eMolecules Medchem Express / Glycolithocholic acid / 5mg / 705860321 / HY-116374 / / 474-74-8 / MFCD00067140 / 433.633 / C26H43NO4
Medchem Express / Glycolithocholic acid / 5mg / 705860321 / HY-116374 / / 474-74-8 / MFCD00067140 / 433.633 / C26H43NO4
Cayman Chemical OlaparIb-d4 500UG
An internal standard for the quantification of olaparib by GC- or LC-MS
Cayman Chemical LenvatInIb-d4 1mg
An internal standard for the quantification of lenvatinib by GC- or LC-MS
Medchemexpress LLC D-Mannitol-13C | 132202-29-0 | 183.16 | 25 MG
D-Mannitol-13C is the 13C labeled version of D-Mannitol. This oral, resistant sugar is widely used in the food and pharmaceutical industries. It promotes calcium and magnesium absorption and retention through cecal fermentation and acts as an osmotic diuretic, reducing tissue edema. D-Mannitol can also enhance brown fat formation, improve insulin effect, and reduce blood sugar levels by initiating the β3-adrenergic receptor (β3-AR), PGC1α, and PKA, which convert white fat cells into brown fat cells. Additionally, it helps maintain osmotic pressure between plant cytoplasm and culture medium and protects cells when the cell wall is weakened or removed.
- Used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes have potential to affect pharmacokinetic and metabolic profiles of drugs.
- Purity of 99.9%.
Medchemexpress LLC Rosiglitazone-d3 | 1132641-22-5 | 97.2% | 360.45 | 1 MG
Rosiglitazone-d3 is the deuterium labeled Rosiglitazone. Rosiglitazone is a selective, orally active PPARγ agonist with EC50s of 30 nM, 100 nM, and 60 nM for PPARγ1, PPARγ2, and PPARγ, respectively. It binds to PPARγ with a Kd of approximately 40 nM and is also an activator of TRPC5 and an inhibitor of TRPM3. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules as tracers for quantitation during drug development. Deuteration has gained attention due to its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
eMolecules Diethyl Malonate-2-13C | 67035-94-3 | MFCD00037508 | 100mg
Toronto Research Chemicals | Diethyl Malonate-2-13C | 100mg | 601594001 | D444421 | | 67035-94-3 | MFCD00037508 | 161.161 | C7H12O4
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Medchemexpress LLC Benzyl Paraben-d7 | 1216916-40-3 | 235.29 | 5 MG
Benzyl Paraben-d7 is a deuterium-labeled Benzyl 4-hydroxybenzoate, which is a prominent material used as an excipient. It can function as a bacteriostatic agent or preservative in pharmaceutical preparations, improving stability, solubility, and processability. Excipients also influence the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs. This product is for research use only and has not been fully validated for medical applications.
- Deuterium-labeled compound
- Can be used as a bacteriostatic agent
- Functions as a preservative
- Improves stability and solubility of pharmaceutical preparations
- Affects ADME processes of co-administered drugs
Medchemexpress LLC Glutaric acid-d4 | 19136-99-3 | 99.5% | 136.14 | 25 MG
Glutaric acid-d4 is a deuterium-labeled form of Glutaric acid. Glutaric acid is a C5 dicarboxylic acid that plays a role as an intermediate in the catabolic pathways of lysine and tryptophan. It has been observed to influence pericyte contractility and migration. Additionally, Glutaric acid is recognized as an indicator for glutaric aciduria type I. This product is intended for research use only.
- Used as a tracer in research applications.
- Suitable as an internal standard for quantitative analysis using techniques such as NMR, GC-MS, or LC-MS.
- Heavy isotopes like deuterium can impact the pharmacokinetic and metabolic profiles of pharmaceutical compounds.
Medchemexpress LLC DL-Proline-d7 | 65807-21-8 | 98.0% | 122.17 | 100 MG
DL-Proline-d7 is the deuterium-labeled form of DL-Proline (HY-W012908). It serves as a biochemical reagent suitable for use as a biological material or organic compound in life science-related research.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by techniques such as NMR, GC-MS, or LC-MS.
- Incorporation of stable heavy isotopes into drug molecules aids in quantitation during the drug development process.
- Deuteration has the potential to influence the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC L-Lysine-d9 hydrochloride | 2708343-64-8 | 191.70 | 5 MG
L-Lysine-d9 (hydrochloride) is a deuterium-labeled form of L-Lysine. L-lysine hydrochloride is an essential amino acid for humans that offers various benefits.
- Used as a tracer.
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Aids in treating herpes.
- Increases calcium absorption.
- Helps reduce diabetes-related illnesses.
- Contributes to improving gut health.
Medchemexpress LLC Acenaphthylene-d8 | 93951-97-4 | 99.5% | 160.24 | 25 MG
Acenaphthylene-d8 is the deuterium labeled Acenaphthylene, a polycyclic aromatic hydrocarbon (PAH). PAHs are derived naturally from coal and tar deposits, and produced by incomplete combustion of organic matter. Deuteration has gained attention due to its potential to affect the pharmacokinetic and metabolic profiles of drugs, making this compound suitable for research applications.
- Deuterium labeled compound
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS